Continuing the schedule of making newer character shards more available on the first Wednesday of every month, later today, Deathpool will replace Anti-Venom as an exclusive to the Premium Orb. Anti-Venom will still be available in the Premium Orb but no longer at the increased drop chance. Anti-Venom will be added to the War Store and the S.H.I.E.L.D. Operative will be removed - you can still find her character shards in the Campaign node of Heroes 4-3.
The inbox message and banner art for the Premium Orb regarding this change were not ready in time for this update today. The banner art will be updated in the near future.